Protein lysine acetylation guards metabolic homeostasis to fight against cancer

Lysine 63-Polyubiquitination Guards against Translesion Synthesis–Induced Mutations

Eukaryotic cells possess several mechanisms to protect the integrity of their DNA against damage. These include cell-cycle checkpoints, DNA-repair pathways, and also a distinct DNA damage-tolerance system that allows recovery of replication forks blocked at sites of DNA damage. In both humans and yeast, lesion bypass and restart of DNA synthesis can occur through an error-prone pathway activate...

The Fight against Cancer

Protein Lysine Acetylation by p300/CBP

Helping Cancer Patients to Fight with Infection

نوتروپنی در صورتی که منجر به شوک عفونی گردد، میتواند باعث مرگ بیمار شود مقابله با عفونت، شامل بررسی دقیق، مراقبت های پیشگیری کننده و مداخله به موقع می باشد. بیماران سرطانی بستری در بیمارستانها، اغلب در معرض خطر عفونت قرار دارند. بویژه اگر احتیاج به درمان شدید با روش های تشخیمی داشته باشند. هرگونه عفونت می تواند تهدیدی برای زندگی بیماران دارای نوتروپنی محسوب شود.

The Fight Against Cervical Cancer

Globally, cervical cancer is one of the most deadly forms of cancer affectingwomen—killingmore than 270,000 people every year. Themajority of these deaths (85%, according to theWHO) occur in developing countries. A global health priority, therefore, is to provide low-cost, highly effective cervical cancer prevention, detection, and control options to all women who need them. The human papilloma...